Oxidative stress and ozone?

Insufficient antioxidant system and then systemic ozone application with „active oxygen“? Doesn’t this increase H2O2, MDA (malondialdehyde) and TH (total hydroperoxides) producing a further oxidative stressor, reducing and/or destroying the antioxidant system already working beyond its capacity in these indications?

In a pharmacological context, we have been able to find clear answers to this and other questions, particularly from research over the last 10 years: in fact, we exert a regulatory influence on a disturbed oxidant/antioxidant balance. Oxidative stress decreases in measurable form as shown by a reduction in MDA, H2O2, TH and a corresponding regulation of the antioxidant systems.